Objective to address terminology and other issues related to thyroid fineneedle aspiration fna, the national cancer institute nci hosted the nci thyroid fna state of the science conference. The 2017 revision of the bethesda system was simultaneously published in thyroid 2017. Recent advances and update of the bethesda system cme faculty. The bethesda system for reporting thyroid cytopathology, 2017.
The 2017 bethesda classification has helped to redefine the various conditions of the thyroid. The bethesda system for reporting thyroid cytopathology tbsrtc is a significant step to standardize the reporting of thyroid fine needle aspiration fna. The clinical team is faced with different risk of malignancies rom associated with for bethesda categories iii to vi, especially iii and iv niftp constitutes a. Further details can be found in the original atlases refs 1 and 2. The bethesda system for reporting thyroid cytopathology tbsrtc1 is now in its second edition. Pdf the 2017 bethesda system for reporting thyroid. Noninvasive follicular thyroid neoplasm with papillarylike nuclear. The bethesda system for reporting thyroid cytopathology will provide the reader with a unified approach to diagnosing and reporting thyroid fna interpretations. In such laboratories, macrophages only often constituted the great majority of nduns cases, with rates that ranged from 15% to. Subcategorisation of ausflus thyroid lesions as per the.
The name comes from the location bethesda, maryland of the conference that established the system. Cibas and ali the bethesda system for thyroid cytopathology parenchyma of the nodule has not been sampled, one cannot exclude a cystic papillary carcinoma. The following document is a short summary of the highlights of the bethesda guidelines. Full text the bethesda system for reporting thyroid cytopathology. Cureus risk stratification of thyroid nodules with bethesda. The original 6 categories remain unchanged, but a number of enhancements have been introduced with the 2017 bsrtc. Journal of pathology and translational medicine 2017. Impact of the modification of the diagnostic criteria in.
Methods this crosssectional study determined the concordance of ultrasound tirads criteria and fine needle aspiration biopsy fna bethesda system in the assessment of the nontoxic thyroid nodule. The conclusions regarding terminology and morphologic criteria from the nci meeting led to the bethesda thyroid atlas project and form the framework for the bethesda system for reporting thyroid. Updates to the bethesda system for reporting thyroid. April 5, 2017 corresponding author mi kyung shin, md, phd department of pathology, hallym university. The bethesda system for reporting thyroid cytology tbsrtc was proposed in 2007 at the national cancer institute thyroid fine needle aspiration state of the art and science. Full text the bethesda system for reporting thyroid. Shienbaum, do, fcap, fascp professor and acting chair department of pathology rowan university school of osteopathic medicine alan j.
Shienbaum, do no disclosures to report learning objectives to understand and apply the bethesda system. The bethesda system for reporting thyroid cytopathology. The bethesda classification was introduced in 2008 to provide standardisation in the evaluation of thyroid fine needle aspiration cytology fnac. Bethesda system thyroid lesion classification systems. The bethesda system for reporting thyroid cytopathology ebook. Cancer cytopathol 2017 niftp ifvptc molecular mostly ras ras. Additionally, the bethesda system is used for cytopathology of thyroid nodules. The bethesda classification for thyroid biopsies is. Nov 01, 2017 highlights of the 2017 bethesda system for thyroid cytopathology. This atlas is the offspring of the the national cancer institute nci thyroid fine needle aspiration fna state of th.
Thyroid cytopathology recent advances october 21, 2017 dr. The first edition of the tbsrtc book was published in 2010 and the second edition in 2018. An attempt has been made to utilize the classification with an example in each category. The bethesda system for reporting thyroid cytopathology 2nd edition pdf. The use of the bethesda system for reporting thyroid. Comparison of thyroid fine needle aspiration biopsy. The 2017 revision described herein was inspired by new data and new developments in the field of thyroid pathology.
Thyroid thyroid cytopathologycytopathology recent advances. A uniform reporting system for thyroid fna will facilitate effective communication among cytopathologists, endocrinologists, surgeons, radiologists, and other health care providers. What is the bethesda system for thyroid cytopathology used. Tbsrtc v1 overview diagnostic category risk of malignancy usual management i. The bethesda classification for thyroid biopsies is effective. Prevalence and associated malignancy of bethesda category iii. The bethesda system for reporting thyroid cytopathology tbsrtc established a standardized, categorybased reporting system for thyroid fineneedle aspiration fna specimens. This can happen when a cyst is aspirated or when the specimen is almost entirely composed of blood. Subcategorisation of ausflus thyroid lesions as per the 2017 bethesda system for reporting thyroid cytopathology.
The second edition bethesda system for reporting thyroid. The bethesda system for reporting thyroid cytopathology tbsrtc established a standardized, categorybased reporting system for thyroid fineneedle. The bethesda system tbs is a system for reporting cervical or vaginal cytologic diagnoses, used for reporting pap smear results. Revised bethesda system for thyroid malignancies ent. Full text pdf files are also available at the official website. For thyroid cytopathology, the 2017 bethesda system cap today. The 2017 revision reaffirms that every thyroid fna report should begin with one of six diagnostic categories, the names of which remain unchanged since they. Methods all thyroid aspirates reported as ausflus over a 4. What is the bethesda system for thyroid cytopathology used in. Cytomorphologic features distinguishing bethesda category iv. Braf bethesda classification mostly aus and sfn mostly sus and m despite differences in the cytological classification and molecular profiles between niftp and ifvptc, the degree of overlap makes it unlikely that most.
Noninvasive follicular thyroid neoplasm with papillarylike nuclear features niftp was only compiled between march 2017 which is when the diagnosis of this. Application of bethesda reporting system of thyroid. Material and methods the study was undertaken in the department of pathology, chirayu medical college and hospital, bhopal during the period from june 2017. Cytological diagnosis of thyroid lesion thyroid lesion of fnac no. Evaluation of thyroid nodules classified as bethesda category iii on cytology and their malignancy rate. Official journal of the american thyroid association 2017, 27 11. The 2017 bethesda system for reporting thyroid cytopathology.
The most appropriate cytological classification of malignancy risk is the bethesda system for thyroid cytopathology. The bethesda system for reporting thyroid cytopathology tbsrtc introduced a new. The 2017 revision reaffirms that every thyroid fna report should begin with 1 of. This study aimed to evaluate the impact of modifying the diagnostic criteria in tbsrtc 2017 at a single institute. Majority of the thyroid cancer nodules n 57, 46% in bethesda vi category followed by bethesda. Noninvasive follicular thyroid neoplasm with papillarylike nuclear features niftp. Thyroid bethesda category ausflus in our microscopes mdpi. It was introduced in 1988 and revised in 1991, 2001, and 2014. Nov 01, 2017 the 2017 revision described herein was inspired by new data and new developments in the field of thyroid pathology. Omed 2017 challenging cases in thyroid cytopathology. Nov 01, 2017 the bethesda system for reporting thyroid cytopathology tbsrtc established a standardized, categorybased reporting system for thyroid fineneedle aspiration fna specimens. Recent concepts in thyroid cytology with emphasis on. Definitions, criteria, and explanatory notes ebook description the first edition of the bethesda system for reporting thyroid cytopathology was published in 2010 and has greatly influenced the practice of thyroid cytopathology. The bethesda system for reporting thyroid cytology tbsrtc.
Subcategorisation of ausflus thyroid lesions as per the 2017. Revised bethesda system for thyroid malignancies ent, head. Niftp and the updated bethesda system for thyroid fna. The bethesda system for reporting thyroid cytopathology bsrtc has standardized the fnac results and. A total of 274 cases were studied over a period of one year 2018 from january to december at a tertiary referral hospital. The 2017 revision reaffirms that every thyroid fna report should begin. The 2017 bethesda system for reporting thyroid cytopathology edmund s. Bethesda categories iii and iv encompass varying risks of malignancy. T1 the 2017 bethesda system for reporting thyroid cytopathology. Table 1 the 2017 bethesda system for reporting thyroid and in many places worldwide and has been endorsed by the cytopathology. To correlate the finding of fnac of thyroid lesions with usg thyroid and estimates the concordance and discordance between two modalities. Cytomorphologic features distinguishing bethesda category. Pdf the bethesda system for reporting thyroid cytopathology. Bethesda classification of thyroid nodule fine needle aspirations i.
Malignancy rates for bethesda iii and iv thyroid nodules. Fnac outcomes are routinely classified using the bethesda system for reporting thyroid cytopathology bsrtc, facilitating appropriate clinical management. Feb 02, 2017 background thyroid nodule is a common disorder of the thyroid. Apr 11, 2021 cytological analysis of fnab specimens is used to estimate malignancy risk. The bethesda system for reporting thyroid cytopathology uniform terminology for reporting thyroid cytopathology involved physicians caring for and managing pts with thyroid nodules associated risk of malignancy rom with diagnostic categories atlas published in 2010. Fineneedle aspiration fna remains the most effective and safe method of evaluating thyroid nodules for potential surgical management. A publication of the american thyroid association thyroid nodules the bethesda classification for thyroid biopsies is effective for clinical management of thyroid nodules final pathology, 4. A changing paradigm in thyroid surgical pathology and implications for thyroid cytopathology. The first edition of the bethesda system for reporting thyroid cytopathology was published in 2010 and has greatly influenced the practice of thyroid cytopathology.
Krane, md phd professor of pathology david geffen school of medicine at ucla. Bethesda system for reporting thyroid cytopathology. Despite their benign nature, they can be associated with multiple pathologic conditions, including thyroid cancer. Revised thyroid bethesda system resets malignant risks clinical endocrinology news, august 10, 2017. It will serve as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists. In these biopsies not enough thyroid cells were obtained to render a diagnosis. Dec 28, 2018 the bethesda system for reporting thyroid cytopathology has recently been revised in 2017 tbsrtc 2017. The present study evaluates the risk of malignancy rom and risk of neoplasm ron among these. The bethesda system for reporting thyroid cytopathology 2nd. The bethesda system for reporting thyroid cytopathology core. The bethesda system for reporting thyroid cytopathology, 2nd ed. Thyroid cytologybethesda classification part 1 youtube. The csc endorses the bethesda system for reporting thyroid cytopathology 2017.
Aims the 2017 bethesda system for reporting thyroid cytopathology tbsrtc recommends subclassification of atypia of undetermined significance ausfollicular lesion of undetermined significance flus into six subcategories. The 2017 revision reaffirms that every thyroid fna report should begin with one of six diagnostic categories, the names of. C professor, department of pathology mcgill university director, cytopathology laboratory. The management guidelines for children with thyroid nodules and differentiated thyroid cancer from the american thyroid association recommends fineneedle aspiration fna as an essential tool for evaluation and management of pediatric thyroid nodules, and the bethesda system for reporting thyroid cytopathology tbsrtc as a guideline to categorize fna cytologic findings. Bethesda system for reporting thyroid cytopathology in. Comparison of thyroid fine needle aspiration biopsy results. Request pdf the 2017 bethesda system for reporting thyroid cytopathology the bethesda system for reporting thyroid cytopathology tbsrtc established a standardized, categorybased reporting. The terminology proposed and illustrated in this text has been widely adopted not only in the u. Evaluation of thyroid nodules classified as bethesda. Notably, aus qualifiers of cannot exclude papillary thyroid carcinoma and cannot exclude follicular neoplasm appear to carry a higher risk of. The 2017 bethesda system for reporting thyroid cytopathology tbsrtc papillary. This accounts for 10 percent of the biopsies, even in the most. Risk stratification of thyroid nodules with bethesda iii. The bethesda system for reporting thyroid cytopathology, 2017 laila khazai 11417.
Nondiagnostic or unsatisfactory cation and provided a uniform template for sharing data cyst. Pdf the bethesda system for reporting thyroid cytology tbsrtc was proposed in 2007 at the national cancer institute thyroid fine. Bethesda classification of thyroid nodule fine needle aspirations. Apr 15, 2020 background fineneedle aspiration cytology fnac has become a wellestablished modality in the diagnosis, staging and followup of thyroid nodules. The nodules of 108 patients were classified as bethesda category iii. The 2017 revision reaffirms that every thyroid fna report should begin with one of six diagnostic categories, the names of which remain. The most common cause for designating cases as ausflus bethesda category iii was the presence of features suggestive of papillary thyroid carcinoma, but not quite fulfilling the criteria for. Pusztaszeri m, rossi ed, auger m, baloch z, bishop j, bongiovanni m, chandra a, cochandpriollet b, fadda g, hirokawa m, hong s. Current practices of thyroid fineneedle aspiration in asia. Ali2 the bethesda system for reporting thyroid cytopathology tbsrtc established a standardized, categorybased reporting system for thyroid. The bethesda system for reporting thyroid cytology tbsrtc was proposed in 2007 at the national cancer institute thyroid fine needle aspiration state of the art and science conference held in. Read the bethesda system for reporting thyroid cytopathology definitions, criteria and explanatory notes by available from rakuten kobo.
Bethesda and bethesda classification systems in the differentiation of benign and malignant thyroid nodules. Bethesda classification of thyroid nodule fine needle. It has high predictive value, reproducibility, and improved clinical significance. Impact of the modification of the diagnostic criteria in the. The risks of malignancy have been recalculated based on post2010 data. Risk stratification of thyroid nodules with bethesda category iii. The 2017 revision reaffirms that every thyroid fna report should begin with one of six diagnostic categories, the names of which remain unchanged since they were first introduced. Application of bethesda reporting system of thyroid cytology. The 2017 revision reaffirms that every thyroid fna report should begin with 1 of 6 diagnostic categories, the names of which remain unchanged since they were first introduced.
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